Comic Life is an excellent bit of software that helps students create very attractive comic strips, using photos, speech bubbles, colourful titles and a large number of layouts. It can be used for story-telling, or story-boarding a film or play, and therefore is useful in a large number of curriculum areas. Recently at the CLC it was used to tell the story of Martin Luther King in history, and also to storyboard the French films about the new school.
See examples 
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The CLC has Comic Life in both large computer rooms, or you can download a 30 day free trial from http://plasq.com/products/ It has both PC and Mac versions.
